Stem Cell Therapy
The Future of Regenerative Medicine is Now!
Today’s patients are becoming more interested in alternative and minimally-invasive treatments, and are more educated with regards to their conditions. As an educated patient, you can feel confident that at OPUS MEDICAL – REGENERATIVE MEDICINE, you are receiving what we believe to be the best stem cell product available on the market today.
By combining stem cells and growth factors, our goal is to promote a longer lasting effect and improve quality of life for those suffering from debilitating disease and disorders.
The stem cells offered at OPUS MEDICAL – REGENERATIVE MEDICINE have been independently tested in-vitro to demonstrate what the product consists of, including growth factors, cell counts, and viability. Our stem cells come from a reliable source, and are carefully controlled by regulated, independent testing.
Stem Cell Therapy Today
Today, doctors in a wide variety of clinical settings include stem cell therapies to treat a myriad of conditions. Typical treatments are simple, safe, do not require anesthesia, and take about the same time as a regular office visit. Stem cells are currently being used in a number of medical applications including, but not limited to, the treatment of:
- Rheumatoid arthritis, Crohn’s disease, lupus and other autoimmune disorders
- Parkinson’s, ALS, Alzheimer’s, Dementia, Autism and other neurological conditions
- Types I and II diabetes
- CHF, PVD, Cardiomyopathy and other heart/circulatory diseases
- Respiratory disorders (COPD)
- Athletic and other orthopedic injuries/conditions
- Fibromyalgia, Neuropathy, Lyme Disease and other chronic medical/pain conditions
- Spinal cord injuries
- Chronic wound management
- Dermatological disorders
- Medical aesthetics
- Sexual health (ED, Peyronie’s, dyspareunia, orgasmic dysfunction)
- Urinary Incontinence, chronic cystitis and other urologic conditions
Stem cells home in on sites of injury/disease by cell signals that attract them there. Once they reach where they need to go, they dock and commence repairing the injury/disease by releasing cytokines, chemokines, and growth factors that aid in hosting endogenous repair.
Immunomodulation and Immunosuppression
Studies have demonstrated the regenerative and immunomodulatory properties of umbilical cord-derived mesenchymal stem cells (UC-MSCs). Numerous peer-reviewed scientific articles have demonstrated the amazing benefits of using stem cells derived from the umbilical cord. Most importantly, they illustrate that these umbilical cord MSCs have immunosuppressive and immunomodulatory properties that allow their use without rejection since the cells do not express HLA-DR. Of note, stem cells derived from the umbilical cord have better immunomodulatory properties than with bone marrow or fat-derived stem cells.
Stem Cells and Osteoarthritis
Mesenchymal stem cells (MSCs) are known to have the potential to regenerate articular cartilage. Studies have shown that intra-articular injection of stem cells provided improved knee function and less pain with no adverse events. Researchers have noticed improvements to both joint function and disease modification with MSC treatment.
MSCs to Treat Diabetes Complications
In one study, intramuscular MSC injection significantly improved the ulcer healing rate for type 2 diabetic patients with critical limb ischemia (CLI) and foot ulcers.
MSCs have also been used to help the body generate more insulin-producing cells, to counteract autoimmunity, and to prevent rejection of allogeneic islet grafts.
Research on Stem Cells and Heart Disease
Stem cells have shown much promise in the treatment of heart disease as stem cells could actually rebuild and replace damaged heart muscle tissue. In a 2012 study on treatments for ischemic cardiomyopathy, patients who received stem cell therapy were observed to have increased functional capacity and improved quality of life.
Stem Cells in the Body
In adulthood, stem cells are easily accessed from our bone marrow and fat tissue. Adult stem cells are considered multipotent stem cells. However, there are drawbacks to using your own stem cells. First, to remove stem cells from your body requires a surgical procedure, which as in every procedure, carries some form of risk, pain, and/or discomfort. Second, stem cells age as we do and their numbers decline substantially with age. Finally, there is scientific evidence illustrating that stem cells from a diseased patient are not as effective as those from a healthy one.
Mesenchymal Stem Cells (MSCs)
MSCs have the ability to migrate and target specific tissues. This property, called “homing”, is an event that allows cells to migrate from a remote area in the body to find a damaged organ or tissue in a specific site. This is the mechanism by which MSCs are infused intravenously and reach the affected areas of the body to perform its regenerative functions.
Experimental models have shown that MSCs have several important functions. They are able to regenerate damaged or injured tissues. In vitro and in vivo studies illustrate the plasticity of MSCs and their ability to give rise to non-hematopoietic cells such as myocytes, tenocytes and nerve cells. MSCs can modulate immune responses because of their specific properties. They are non-immunogenic cells that express few major histocompatibility complex class I antigens (MHC I) and do not express either major histocompatibility complex class II antigens (MHC II) or costimulatory molecules, rendering them incapable of activating a T-cell response.
They regulate the immune system by increasing the response of regulatory T-cells and decreasing pro-inflammatory mediators such as TNF-α, and IFN-γ. Thus, MSCs may be used from an unrelated donor. MSCs have been approved for pediatric graft vs host disease and are in clinical studies for adult indications of such. The use of MSCs for graft vs host disease clearly demonstrates that MSCs are safe for allogeneic use.
MSCs work in a paracrine manner to aid in host endogenous repair. MSCs release growth factors and proteins to communicate and affect neighboring cells. Studies illustrate a host of cytokines, chemokines, and growth factors released by MSCs such as VEGF, FGF, PDGF, and SCF, to name a few. Growth factor release such as that of VEGF helps in the formation of new vascularization or angiogenesis while release of IL-1ra aids in suppressing the pro-inflammatory response of TNF-α. Hence, MSCs work in various methods to aid in healing and natural repair.
The regenerative medicine product offered at OPUS MEDICAL – REGENERATIVE MEDICINE contains stem cells and growth factors which are beneficial for repair, growth, and healing. The release of the growth factors aids in the formation of new blood vessels, activation of endogenous stem cells, modulation of the immune system, and growth of cells and tissue.
Commitment to Quality & Safety
We use only umbilical cord-derived regenerative medicine products. This causes no pain for the patient as there is no extraction or procedure required to obtain the stem cell-based product.
Most importantly, our regenerative medicine product is minimally manipulated, preserving its natural healing properties.
Our regenerative medicine UC-MSCs yield consistent concentrations allowing for multiple administrations in uniform, high-cell-count doses. Patients can enjoy safe, non-surgical treatments in the time it would take them for a traditional office visit.
If you’re considering stem cell therapy, please contact us at OPUS MEDICAL – REGENERATIVE MEDICINE. You will have a personal one-on-one free consultation with Dr William Clark to discuss your current condition and treatment options. We look forward to helping you achieve your healthcare goals and improve your quality of life.